Research in Kirsten Jung’s lab focuses on elucidating the molecular mechanisms of stimulus perception under acid stress in Escherichia coli and other γ-proteobacteria. We study the uptake, excretion and homeostasis of primary metabolites, such as pyruvate, in Escherichia, Salmonella and Vibrio. We elucidate the role of RNA modifications during abiotic and biotic stress response in Escherichia and Vibrio. We also investigate translation elongation factor P (EF-P), a protein that alleviates ribosome stalling at polyproline stretches, and its post-translational modification systems. Last but not least, we are working on identifying new intracellular targets of natural compounds, such as stress hormones.