Dept. of Medical Microbiology and Hospital Epidemiology
Max von Pettenkofer Institute
LMU Munich
Pettenkoferstr. 9a
80336 München
Helicobacter pylori and related Helicobacter spp., Campylobacterales, other GI pathogens and the GI microbiota
Bacterial genomics, transcriptomics, „methylomics“. Combination of wet lab (Illumina/PacBio/Nanopore sequencing, mutagenesis and mutant/complementant phenotypical characterization, genetic and biochemical approaches) and computational methods in the field of bacterial genomics
We have a long-standing interest in the evolution of bacteria that cause diseases of the gastrointestinal tract. We are interested both in global phylogeographic population structure as well as within host evolution and adaptation to different ecological niches and the relative contributions of mutation and recombination to bacterial diversification. Lately, we have also become interested in „bacterial epigenetics“, the diverse methylation patterns generated by highly variable portfolios of methyl transferases and the functional implications of this added layer of diversity.